What is HDL cholesterol?

What is HDL cholesterol?

High-density lipoprotein is abbreviated as HDL.

It’s also sometimes called “good” cholesterol. It is considered good because it carries excess cholesterol from tissues to the liver, which then removes the cholesterol from the body. You want to have lower levels of LDL, but you want to have higher levels HDL. Lower levels of HDL raise the risk of heart disease.1,2

A lower HDL level increases the risk of heart disease, so you want to have higher HDL numbers.
Lower HDL, Higher risk

What are the risks of low HDL?

If there is too little HDL in the blood, there is not enough to carry LDL to the liver for disposal.3 Excess LDL accumulates as plaque on artery walls and increases the risk of heart disease.3

What factors impact HDL levels?

The factors that affect HDL levels are similar to those that affect LDL levels.

Genetics4
Smoking4
Weight and activity level1,4
Gender (women tend to have higher HDL levels than men)4
Diabetes4

How do you know if you have low HDL cholesterol?

The recommended way to find out if you have low HDL cholesterol is through a blood test called a lipoprotein profile.1 After a 9- to 12-hour fast, your doctor will take a small sample of blood for the test to determine your cholesterol level.1

What do your cholesterol
numbers mean?

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What is
NIASPAN?

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*Up to $70 maximum savings per month for NIASPAN.

Or your state’s language.

Eligibility: Available to patients with commercial prescription insurance coverage for NIASPAN, TRILIPIX, or TRICOR who meet eligibility criteria. Copay assistance program is not available to patients receiving prescription reimbursement under any federal, state, or government-funded insurance programs (for example, Medicare [including Part D], Medicare Advantage, Medigap, Medicaid, TRICARE, Department of Defense, or Veterans Affairs programs) or where prohibited by law or by the patient’s health insurance provider. If at any time a patient begins receiving prescription drug coverage under any such federal, state, or government-funded healthcare program, patient will no longer be able to use the NIASPAN, TRILIPIX, or TRICOR Savings Card and patient must call Customer Service at 844.415.0681 to stop participation. Patients residing in or receiving treatment in certain states may not be eligible. Patients may not seek reimbursement for value received from the NIASPAN, TRILIPIX, or TRICOR Savings Card from any third-party payers. Offer subject to change or discontinuance without notice. Restrictions, including monthly maximums, may apply. This is not health insurance. Please see full Terms and Conditions.

Terms and Conditions

Pharmacist instructions:

  • Please submit the copay card authorized for all commercially insured patients by the patient’s primary insurance as a secondary transaction to Customer Service.
  • When you use this card, you are confirming that you have not submitted and will not submit a claim for this prescription for reimbursement under any federal, state, or government-funded healthcare program, such as Medicare (including Part D), Medicare Advantage, Medigap, Medicaid, TRICARE, Department of Defense, or Veterans Affairs programs.
  • Pharmacists with questions, please call Customer Service at 844.415.0681.

USES and IMPORTANT SAFETY INFORMATION You Should Know About NIASPAN® (niacin extended-release) tablets5

Uses

NIASPAN® (niacin extended-release) tablets are a prescription medication used along with diet when a low-cholesterol diet and exercise alone are not enough.

  • NIASPAN raises HDL (“good”) cholesterol and lowers LDL (“bad”) cholesterol and triglycerides in people with abnormal cholesterol levels.
  • NIASPAN is also used to lower the risk of heart attack in people who have had a heart attack and have high cholesterol.
  • In people with coronary artery disease and high cholesterol levels, NIASPAN, when used with a bile acid-binding resin (another cholesterol medicine), can slow down or lessen the buildup of plaque (fatty deposits) in your arteries.

Taking NIASPAN with another cholesterol-lowering medicine (simvastatin) does not reduce heart attacks or strokes more than taking simvastatin alone.

Important Safety Information

  • NIASPAN is not for people with liver problems, stomach ulcers, serious bleeding problems, or those allergic to any product ingredient.
  • Severe liver damage has occurred when switching to a long-acting niacin (NIASPAN) from immediate-release niacin. Do not switch between forms of niacin without talking to your healthcare provider.
  • Tell your healthcare provider about any unexplained muscle pain, tenderness, or weakness, as this could be a sign of a serious side effect. This risk increases when NIASPAN is taken, particularly in the elderly, diabetics, and those with kidney or thyroid problems.
  • NIASPAN should be used with caution if you consume large amounts of alcohol and/or have a past history of liver disease.
  • Your healthcare provider should do blood tests before and during treatment to check liver enzyme levels, as these can increase with treatment.
  • NIASPAN can cause an increase in blood sugar levels. If you have diabetes, check your blood sugar levels more frequently during the first few months or with NIASPAN dose changes.
  • Tell your healthcare provider if you have kidney problems or a history of gout. NIASPAN can cause an increase in uric acid levels.
  • The most common side effects with NIASPAN are flushing, diarrhea, nausea, vomiting, increased cough, and itching.
  • Flushing (warmth, redness, itching, and/or tingling of the skin) is a common side effect of NIASPAN therapy. It may vary in severity and is more likely to happen when starting NIASPAN or during dose increases. Flushing may get better after several weeks of consistent NIASPAN use. Talk to your doctor about how the symptoms of flushing are different from symptoms of a heart attack. By dosing at bedtime, flushing will likely occur during sleep. If awakened by flushing, get up slowly, especially if feeling dizzy or faint, or taking blood pressure medications.
  • If you are taking another cholesterol medication called a bile acid-binding resin (e.g., colestipol, cholestyramine) along with NIASPAN, take these medicines at least 4 to 6 hours apart.
  • Some medicines should not be taken with NIASPAN. Tell your healthcare provider about all the medicines you take, including aspirin, any cholesterol medication, blood pressure medication, blood thinner medication, or any products containing niacin or nicotinamide.

For more information, talk with your healthcare provider.

References: 1. US Department of Health and Human Services, National Institutes of Health, National Heart, Lung, and Blood Institute. Your Guide to Lowering Your Cholesterol With TLC. NIH publication No. 06-5235. https://www.nhlbi.nih.gov/files/docs/public/heart/chol_tlc.pdf. Published December 2005. Accessed May 14, 2018. 2. Mayo Clinic. High cholesterol. https://www.mayoclinic.org/diseases-conditions/high-blood-cholesterol/symptoms-causes/syc-20350800. Accessed May 14, 2018. 3. WebMD. HDL cholesterol: the good cholesterol. https://www.webmd.com/cholesterol-management/guide/hdl-cholesterol-the-good-cholesterol#1. Accessed May 15, 2018. 4. American Heart Association. What your cholesterol levels mean. http://www.heart.org/HEARTORG/Conditions/Cholesterol/AboutCholesterol/What-Your-Cholesterol-Levels-Mean_UCM_305562_Article.jsp#.WoXr-HxMGM8. Updated May 3, 2018. Accessed May 15, 2018. 5. NIASPAN [package insert]. North Chicago, IL: AbbVie Inc.

Please see the full Prescribing Information for NIASPAN and discuss it with your healthcare provider.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

If you cannot afford your medication, contact www.pparx.org for assistance.

*Up to $70 maximum savings per month for NIASPAN.

Or your state’s language.

Eligibility: Available to patients with commercial prescription insurance coverage for NIASPAN, TRILIPIX, or TRICOR who meet eligibility criteria. Copay assistance program is not available to patients receiving prescription reimbursement under any federal, state, or government-funded insurance programs (for example, Medicare [including Part D], Medicare Advantage, Medigap, Medicaid, TRICARE, Department of Defense, or Veterans Affairs programs) or where prohibited by law or by the patient’s health insurance provider. If at any time a patient begins receiving prescription drug coverage under any such federal, state, or government-funded healthcare program, patient will no longer be able to use the NIASPAN, TRILIPIX, or TRICOR Savings Card and patient must call Customer Service at 844.415.0681 to stop participation. Patients residing in or receiving treatment in certain states may not be eligible. Patients may not seek reimbursement for value received from the NIASPAN, TRILIPIX, or TRICOR Savings Card from any third-party payers. Offer subject to change or discontinuance without notice. Restrictions, including monthly maximums, may apply. This is not health insurance. Please see full Terms and Conditions.

Terms and Conditions

Pharmacist instructions:

  • Please submit the copay card authorized for all commercially insured patients by the patient’s primary insurance as a secondary transaction to Customer Service.
  • When you use this card, you are confirming that you have not submitted and will not submit a claim for this prescription for reimbursement under any federal, state, or government-funded healthcare program, such as Medicare (including Part D), Medicare Advantage, Medigap, Medicaid, TRICARE, Department of Defense, or Veterans Affairs programs.
  • Pharmacists with questions, please call Customer Service at 844.415.0681.

If you have any questions about AbbVie’s NIASPAN.com website that have not been answered, click here. This website and the information contained herein is intended for use by U.S. residents only, is provided for informational purposes only, and is not intended to replace a discussion with a healthcare provider. All decisions regarding patient care must be made with a healthcare provider and take into consideration the unique characteristics of each patient.

USES and IMPORTANT SAFETY INFORMATION You Should Know About NIASPAN® (niacin extended-release) tablets5

Uses

NIASPAN® (niacin extended-release) tablets are a prescription medication used along with diet when a low-cholesterol diet and exercise alone are not enough.

  • NIASPAN raises HDL (“good”) cholesterol and lowers LDL (“bad”) cholesterol and triglycerides in people with abnormal cholesterol levels.
  • NIASPAN is also used to lower the risk of heart attack in people who have had a heart attack and have high cholesterol.
  • In people with coronary artery disease and high cholesterol levels, NIASPAN, when used with a bile acid-binding resin (another cholesterol medicine), can slow down or lessen the buildup of plaque (fatty deposits) in your arteries.